... It is not real, it is not a process, nor is it even a matter of current theoretical speculation. It is artifact of decision making with incomplete...
... a population (e.g. public health) then statistical models may be used as descriptive tools -- there is no need or occasion to invoke "stochasticity"...">> ...
... a population (e.g. public health) then statistical models may be used as descriptive tools -- there is no need or occasion to invoke "stochasticity"...">> ...
... Moreover, Wout points out that the approach to experimental design -- using inbred strains, age-matched animals, controlling environment and exposures as...
As requested by dr Lipscomb, I have made a power point presentation, that I would like to present and discuss with you tomorrow. I hope to make clear that the...
I apologize: I made a small, but crucial error in my announcement, it should have been: I hope to make clear that the problem that I put forward in my...
We would like to remind you of this upcoming event. DRSG Teleconference **Time Change** Date: Tuesday, March 5, 2002 Time: 12:30PM - 1:30PM EST (GMT-05:00) ...
One small additional point: Wout has shown, it seems to me, that for conventional toxicity tests, no single set of observations contains enough information to...
I am forwarding announcements for job openings at NCEA at two different levels in the area of PBPK modeling. If interested, please respond to the name/address...
Just a reminder, DRSG teleforum will take place today, March 5, from 12:30 -1:30 PM (Eastern. The speaker for today's teleforum will be Dr. Wout Slob from...
Dear collegues, I enjoyed the teleconference discussion yesterday, and only regret that it was so short - but that was my own fault, I had underestimated the...
Wout, On behalf of the DRSG, I would like to thank you for your presentation yesterday. Although we had limited time for discussion, I hope you don't mind if...
233
DRSG@yahoogroups.com
Mar 6, 2002 2:08 pm
We would like to remind you of this upcoming event. DRSG Teleconference **Time Change** Date: Tuesday, March 5, 2002 Time: 12:30PM - 1:30PM EST (GMT-05:00) ...
To clarify my point: the problem I see with using an individual's own background as the basis for estimating the percent change is that often we don't know...
... endpoint) do we find acceptable? This is both a toxicology and a policy issue (as also put forward by Clark). CDC: I am more inclined to think of...
TO: Wout Slob, Clark Carrington, DRSG From: Jim Wilson Re: Two of three issues, as posed by CDC. Re Issue 1: I would agree with CDC that the decision is...
Colleagues, From my immediately previous note you will conclude that I believe that Wout Slob's finding is of central importance to toxicologic risk...
238
Sandra Baird
sbaird@...
Mar 12, 2002 4:38 pm
Great Idea Jim-- Then the DRSG should take it to the Society of Toxicology! It might also be interesting (and inflammatory) to ask Kevin Brand to present his...
Dr. Baird: While I would agree that the effect of experimental error on understanding dose-response relationships is not readily apparent, I seriously doubt...
240
Sandra Baird
sbaird@...
Mar 12, 2002 7:56 pm
RE: [DRSG] Experimental error in toxicology testsDr. Schwab-- I admit that I framed my comment in a cavalier manner. However, I believe that all of us are...
241
Kevin Brand
kbrand@...
Mar 13, 2002 12:36 am
Dear DRSG, Sandy kindly suggested that it may be `interesting (and inflammatory)' to ask me to talk about the research on toxicity ratios that I have done ...
Paul: Now I understand your point. I think this is really the heart of the whole problem. Of course we cannot measure each individual's background (in...
Some comments to Clark's response: CDC: But, for the same reasons, one would doubt the relevancy of an animal experiment to humans. If you just use the ED50...
244
Kevin Brand
kbrand@...
Mar 14, 2002 3:59 pm
Dear DRSG, Wout parenthetically notes: Variation in NOAELs between studies is too much polluted by noise in the NOAELs themselves, and therefore doing this...
245
Kevin Brand
kbrand@...
Mar 14, 2002 4:45 pm
Whoops! It was pointed out that I gave you the same reference twice. Thanks Sandy. The two (different!:) references are. Brand KP, L. Rhomberg and JS Evans,...
Kevin, Your response was helpful in refreshing my memory regarding the censoring problem. I used the word "noise" in the NOAELs themselves, which is indeed not...
248
Kevin Brand
kbrand@...
Mar 15, 2002 8:01 pm
Dear Wout and DRSG, I would like to briefly respond to the last part of Wout's latest exchange (I would like to respond to the first part, but have an ...
249
Kevin Brand
kbrand@...
Mar 15, 2002 10:28 pm
Dear Wout and DRSG, I intersperse my response below. Thanks Wout for your comments. Cheers, Kevin ... censoring ... indeed ... to ... is [KB] I whole...
251
DRSG@yahoogroups.com
Mar 26, 2002 8:32 pm
We would like to remind you of this upcoming event. DRSG Teleconference Date: Tuesday, April 2, 2002 Time: 3:30PM - 4:30PM EST (GMT-05:00) (The time is Easter...
254
Justin Teeguarden
jteeguarden@...
Apr 1, 2002 4:47 pm
<<DRSG-StdntAwrd02.pdf>> DRSG Membership: The Dose-Response Specialty Group of the Society for Risk Analysis is advertising for this years student poster award...
