There are two critical periods concerning President Kennedy's efforts to gain access to classified UFO files. The first, according to leaked Majestic documents, began on June 28, 1961 when Kennedy formally requested DCI Allen Dulles to review MJ-12 activities as they related to Cold War psychological warfare plans. This period ended with Dulles departure as DCI on November 29, 1961 when a top secret set of MJ-12 directives contained in the leaked "burned memo" were finalized in response to Kennedy's inquiries. The second period began on September 20, 1963 when President Kennedy gave a speech at the UN General Assembly calling for joint space and lunar missions with the USSR. In the subsequent two months up to his assassination, President Kennedy conducted a high risk political dialogue with Soviet Premier Nikita Khrushchev to reach broad agreement on future space and lunar cooperation. Shortly before or on November 12, 1963, Kennedy and Khrushchev finally reached agreement. Included within the scope of their agreement was the release of classified UFO files to NASA and sharing these with the USSR as a vital security component. This resulted in a series of executive actions by Kennedy on November 12 to formalize the release of UFO files to ensure space cooperation. This triggered a response by CIA counterintelligence based on the MJ-12 directives finalized in the final months of Dulles tenure. In this presentation, I will outline the timeline of events pertaining to Kennedy's efforts to declassify UFO files; analyze historic events and documents that cast light on claims found in the majestic documents; and outline the critical role of James Jesus Angleton in implementing the MJ-12 directives and the Kennedy assassination.