The problem of malignancy in lower extremity ulcers really seems to be
underestimated. In 2000-2001 similar alerts were published in European
Wound Management Association materials. The file is here:
http://www.ewma.org/pdf/spring01/05-MalignancyAndPre-
malignancyInLegUlceration.pdf

Now I understood that I must refer a patient with leg ulcer whom I
treat unsuccessfully for 3 weeks to wound biopsy.

Isabelle, we all wish good luck to you!
Oleg.