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Sonne 9 as a substitute for CSM???   Message List  
Reply | Forward Message #4112 of 4116 |
Lignan From Flax Seed: An Alternative to Cholestyramine?

bg,

I know this isn't exactly comparing apples to apples, but I found
this study on PubMed about CSM binding hormones, and they studied
other substances that did it, too. The second best substance next to
CSM was lignin. Lignin is found in pretty high concentrations in
flax seed. So, I'm wondering if ground flax seed would be a good,
economical option to CSM? The study also talks about a few other
forms of fiber, too. I've cut and pasted it below, and here's the
link:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
cmd=Retrieve&db=PubMed&list_uids=3010251&dopt=Abstract

Susannah

In vitro binding of steroid hormones by natural and purified fibers.

Shultz TD, Howie BJ.

The in vitro binding of estrone, estradiol-17 beta, estriol,
testosterone, dihydrotestosterone, and estrone-3-glucuronide by
wheat, oat, and corn brans, oat hulls, cellulose, lignin, and
cholestyramine resin was measured. The extent of steroid
sequestration was characteristic and reproducible for each hormone.
Cholestyramine bound an average of 90% of all the steroids tested,
whereas cellulose bound the least (12%). Of the other substances
tested, each bound the following percentage of unconjugated hormones:
lignin, 87%; wheat and oat brans, 45% each; corn bran 44%; and oat
hulls, 32%. The conjugated steroid was less likely to bind than the
unconjugated steroids. Lignin appeared to be an important component
in the interaction with steroid hormones. The results support the
hydrophobic nature of adsorption and suggest that the components of
fiber in diet should be considered separately when evaluating in vivo
metabolic effects.






Tue Jan 27, 2004 8:03 pm

cjmsbj
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Message #4112 of 4116 |
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I've saved this former post in my files, thinking it just might be a good product to incorporate into my supplements, since this could help with ridding the...
bsgttx
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Jan 18, 2004
5:01 pm

bg, I know this isn't exactly comparing apples to apples, but I found this study on PubMed about CSM binding hormones, and they studied other substances that...
Susannah Martin
cjmsbj
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Jan 28, 2004
5:09 pm
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