--- In klinefelterssyndromesgateway@yahoogroups.com, Sabrina Syvarth
<angelsab1977@...> wrote:


"Are you telling me that you suddenly developed KS later in life?"


You might want to do a little basic research on the etiology of
genetic mutations before shooting your mouth off any further.

Assuming for the sake of argument that BPA has some role in at least
some cases of KS (I can't speak to that because I haven't researched
it), you are making a huge and pretty stupid assumption by acting as
if it could only affect a person exposed to it after they were born...

it is entirely possible and quite common for genetic mutations to
result from chemical (and radiation) exposure affecting the genetic
material contained in sperm and eggs, so that any resulting embryo
conceived from that material will carry the mutation.

This is why many drugs and chemicals carry warnings about exposure to
pregnant women or those who *might* become pregnant, as it can cause
birth defects, many of which involve intersex conditions.

In the case of 47 XXY, the extra X chromosome is the result of faulty
sex cell division (meiosis) leaving one too may X chromosomes in the
reproductive material (usually the egg) that is then passed on to the
offspring.

And a simple google search shows that there *is* research that
strongly suggests that BPA can disrupt normal sex cell meiosis-

http://www.google.com/search?q=BPA+%2Bmeiosis

So it is perfectly within the realm of possibility that BPA could be
responsible for at least some cases of KS, not by turning XY
individuals into XXY individuals after they are born, but by causing
the genetic material that makes up that individual to be damaged
before they are even conceived.