PragaTI (TI India Technical University) announces a seminar in association with

VLSI Society of India

Automated Design of Digital Microfluidic Lab-on-Chip

Connecting Biochemistry to Information Technology and Electronic Design Automation

11 February, 2009|11:00AM-12:00PM

Venue – Texas Instruments, Bangalore Campus

Bagmane Tech Park, CV Raman Nagar, Bangalore 560093

by

Krishnendu Chakrabarty

Professor,

Dept of Electrical & Computer Engineering, Duke University

Target Audience

The seminar is open to anyone who is interested in the area of medical electronics, and associated EDA.

Objective

To provide an overview, and update on the design of Lab-on-Chip devices.

Abstract

Microfluidics-based biochips (or lab-on-chip) are revolutionizing laboratory procedures in molecular biology, and leading to a convergence of information technology with biochemistry and microelectronics. Advances in microfluidics technology offer exciting possibilities for high-throughput DNA sequencing, protein crystallization, drug discovery, immunoassays, neo-natal and point-of-care clinical diagnostics, etc. As microfluidic lab-onchip mature into multifunctional devices with "smart" reconfiguration and adaptation capabilities, automated design and ease of use become extremely important. Computer-aided design (CAD) tools are needed to allow designers and users to harness the new technology that is rapidly emerging for integrated biofluidics. This talk will present ongoing work on design and test techniques for microfluidic biochips. First, the speaker will provide an overview of electrowetting-based digital microfluidic biochips. Next, the speaker will describe synthesis tools that can map behavioral descriptions to a reconfigurable microfluidic device and generate an optimized schedule of bioassay operations, the binding of assay operations to functional units, and the layout and droplet flow-paths for the biochip. Techniques for pin-constrained chip design, fault detection, and dynamic reconfiguration will also be presented. An automated design flow allows the biochip user to concentrate on the development of nano, and micro-scale bioassays, leaving implementation details to CAD tools.

Krishnendu Chakrabarty received the B. Tech. degree from the Indian Institute of Technology, Kharagpur, in

1990, and the M.S.E. and Ph.D. degrees from the University of Michigan, Ann Arbor, in 1992 and 1995,

respectively, all in Computer Science and Engineering. He is now Professor of Electrical and Computer

Engineering at Duke University. Dr. Chakrabarty is a recipient of the National Science Foundation Early

Faculty (CAREER) award, the Office of Naval Research Young Investigator award, the Humboldt Research

Fellowship from the Alexander von Humboldt Foundation, Germany, and several best papers awards at IEEE

conferences. His current research projects include: testing of system-on-chip integrated circuits; microfluidic

biochips; wireless sensor networks. He has authored seven books on these topics, and published over 250

papers in journals and refereed conference proceedings.

Prof. Chakrabarty is a Distinguished Visitor of the IEEE Computer Society for 2005-2007 and a Distinguished Lecturer of

the IEEE Circuits and Systems Society for 2006-2007. He is an Associate Editor of IEEE Transactions on Computer-Aided Design

of Integrated Circuits and Systems, IEEE Transactions on VLSI Systems, IEEE Transactions on Circuits and System I, IEEE

Transactions on Biomedical Circuits and Systems, and ACM Journal on Emerging Technologies in Computing Systems. He is

an Editor of IEEE Design & Test of Computers and of the Journal of Electronic Testing: Theory and Applications (JETTA). Prof.

Chakrabarty is a senior member of IEEE, a senior member of ACM, and a member of Sigma Xi.

More information about the speaker can be found on http://people.ee.duke.edu/~krish/

Registration close & withdrawal date: 6-Feb-09

The seminar is open to all members of VSI. Contact VSI secretariat (vsisecy@...) with details of your name VSI membership number, nationality, and organization no later than Feb 9 (5.00 PM IST). You must carry an organizaitonal photo-id and arrive at least 15 minutes before the event begins to go through security.